ISSN 1662-4009 (online)

ey0016.2-5 | Neonatal Hypoglycaemia | ESPEYB16

2.5. Diagnosis and management of hyperinsulinaemic hypoglycaemia

S Galcheva , S Al-Khawaga , K Hussain

To read the full abstract: Best Pract Res Clin Endocrinol Metab. 2018 Aug;32(4):551–573.This review provides a state of the art in the field of hyperinsulinaemic hypoglycemia (HH). The physiology of insulin secretion is discussed followed by the classification of the different subtypes of HH and then a detailed description of all the monogenic forms of HH. Novel forms of HH, such as...

ey0017.2-12 | Updates on the Genetics of Neonatal Diabetes Mellitus, Congenital Hyperinsulinism and Glucose Disorders | ESPEYB17

2.12. Ion Transporters, channelopathies, and glucose disorders

H Demirbilek , S Galcheva , D Vuralli , S Al-Khawaga , K Hussain

To read the full abstract: Int J Mol Sci. 2019 May 27;20(10). pii: E2590. doi: 10.3390/ijms20102590. PMID:31137773.Ion channels and transporters play essential roles in excitable cells, including cardiac, skeletal and smooth muscle cells, neurons, and endocrine cells. In pancreatic beta-cells, KATPchannels link the metabolic signals generated inside the cell to changes in the beta-cell membra...